What Is Imipramine? What are its uses?

Imipramine is an antidepressant drug belonging to the class of tricyclic drugs (TCAs). TCAs is a class of drugs used for treating Depression , panic disorders and post-traumatic disorder. Imipramine is thought to work by blocking chemicals in the mind, which makes it easier to deal with depression.

Imipramine is a drug that has undergone extensive research and it's considered to be effective for treating Anxiety and depression. Imipramine may improve sleep, decrease fatigue and aid in weight loss. Imipramine can also be prescribed for chronic pain, fibromyalgia and irritable Bowel Syndrome (IBS).

Imipramine: What are the Benefits?

Imipramine has been shown to be an effective depression treatment in studies . In a 2020 JAMA Psychiatry study , Imipramine proved to be more effective than placebo in treating adults with major depression disorder. Imipramine significantly improved symptoms in the study participants compared with those who were taking placebo.

Imipramine may also be helpful in treating mental disorders such as OCD, panic attacks, PTSD and ADHD. Off-label, the drug can also be prescribed for conditions such as chronic pain and bedwetting.

Imipramine Side Effects

Imipramine can have some unwanted side effects, even though It Is well tolerated. Side effects can include blurred vision and drowsiness. Imipramine may also have sexual side effects such as decreased orgasm and libido.

Some of the less common, but serious, side effects include confusion, hallucinations and irregular heartbeat. Serotonin Syndrome, which can be life-threatening, is a condition that occurs when the body produces too much serotonin.

Patients taking Imipramine are advised to discuss potential side effects of the medication with their doctors. Report any change in mood or behavior that occurs while on the drug.

Imipramine: Experts' and professionals' opinions

Imipramine, according to most experts, is a treatment that works for mental disorders like depression. They caution, however, that Imipramine should be taken only when all other treatment options have failed. Imipramine may not be recommended if you are pregnant or nursing.

Imipramine is also habit-forming, and experts warn that it should not be used for prolonged periods without medical supervision. Experts recommend that those who take Imipramine be closely monitored for signs of abuse and addiction.

Imipramine: How To Start?

Your doctor will probably start you off on a small dose of Imipramine and increase the dosage as necessary. Imipramine should be taken exactly as prescribed. Do not change the dosage of Imipramine without consulting your doctor. Avoid drinking alcohol when taking Imipramine as this can cause side effects.

Imipramine may interact with other drugs. Included are prescription, over-the counter, herbal, vitamin, and other supplements.


Imipramine can be used to treat depression, anxiety and many other conditions. Imipramine can improve your mood, energy, and sleep levels. It also reduces fatigue and helps you lose weight. Imipramine may cause some side effects. It is therefore important that you discuss these risks with your physician before beginning treatment.